Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis...
AbstractBackgroundFebrile neutropenia (FN) occurs following myelosuppressive chemotherapy and is associated with morbidity, mortality, costs, and chemotherapy reductions and delays. Granulocyte...
View ArticleUsing resource modelling to inform decision making and service planning: the...
AbstractBackgroundOrganised colorectal cancer screening is likely to be cost-effective, but cost-effectiveness results alone may not help policy makers to make decisions about programme feasibility or...
View ArticleEffectiveness and cost-effectiveness of an awareness campaign for colorectal...
AbstractBackground A campaign to increase the awareness of the signs and symptoms of colorectal cancer (CRC) and encourage self-presentation to a GP was piloted in two regions of England in 2011....
View ArticleEvaluating a computer aid for assessing stomach symptoms (ECASS): study...
AbstractBackgroundFor most cancers, only a minority of patients have symptoms meeting the National Institute for Health and Clinical Excellence guidance for urgent referral. For gastro-oesophageal...
View ArticleCost-effectiveness of screening for ovarian cancer amongst postmenopausal...
AbstractBackgroundThe United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) was the biggest ovarian cancer screening trial to date. A non-significant effect of screening on ovarian...
View ArticleDegarelix for Treating Advanced Hormone-Dependent Prostate Cancer: An...
AbstractAs part of its Single Technology Appraisal Process, the National Institute for Health and Care Excellence (NICE) invited the manufacturer of degarelix (Ferring Pharmaceuticals) to submit...
View ArticleA New Approach for Sampling Ordered Parameters in Probabilistic Sensitivity...
AbstractBackgroundProbabilistic sensitivity analysis (PSA) in cost-effectiveness analysis involves sampling a large number of realisations of an economic model. For some parameters, we may be uncertain...
View ArticleFactors associated with completion of bowel cancer screening and the...
AbstractBackground:The primary colorectal cancer screening test in England is a guaiac faecal occult blood test (gFOBt). The NHS Bowel Cancer Screening Programme (BCSP) interprets tests on six samples...
View ArticleCalibrating Natural History of Cancer Models in the Presence of Data...
AbstractThe calibration of cancer natural history models is often challenged by a lack of representative calibration targets, forcing modellers to rely on potentially incompatible datasets. Using a...
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